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Abstract #3957

Contrast-Enhanced MDCT Vs. Time-Resolved MR Angiography Vs. Contrast-Enhanced Perfusion MRI: Assessment of Treatment Response by Patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Yoshiharu Ohno1, 2, Mizuho Nishio1, Hisanobu Koyama1, 2, Takeshi Yoshikawa1, Sumiaki Matsumoto1, Daisuke Takenaka1, Katsusuke Kyotani2, Nobukazu Aoyama2

1Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 2Radiology, Kobe University Hospital, Kobe, Hyogo, Japan; 3Philips Electronics Japan, Tokyo, Japan; 4Philips Healthcare Asia Pacific, Tokyo, Japan; 5Department of Medical Engineering, Division of Allied Health Sciences, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

In the last several years, dynamic CE-perfusion MRI and time-resolved CE-MR angiography have been put forward as new techniques for quantitative and qualitative assessment of pulmonary vascular diseases. However, there have been no reports on the potential of perfusion MRI and time-resolved MR angiography for assessment of therapeutic effects on CTEPH patients. We hypothesized that dynamic CE-perfusion MRI has equal to or better potential for therapeutic assessment than others in CTEPH patients. The aim of our study was therefore to directly compare the therapeutic effect assessment capability of CE-MDCT, time-resolved CE-MR angiography and dynamic CE-perfusion MRI for CTEPH patients.