Abstract #3967

T2* Measurements of 3 T MRI with Ultra-Short TE: Capability of Assessments for Pulmonary Functional Loss and Disease Severity in Patients with Connective Tissue Disease (CTD)

Yoshiharu Ohno¹,², Mizuho Nishio¹, Hisanobu Koyama¹,², Masaya Takahashi³, Takeshi Yoshikawa¹, Sumiaki Matsumoto¹, Daisuke Takenaka¹, Katsusuke Kyotani²

¹Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; ²Radiology, Kobe University Hospital, Kobe, Hyogo, Japan; ³Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; ⁴Philips Electronics Japan, Tokyo, Japan; ⁵Philips Healthcare Asia Pacific, Tokyo, Japan

CT is most widely used for radiological assessment of disease severity in CTDs. Recently, we have tried to determine the utility of regional T2* measurement in the lung for assessment of pulmonary diseases. We hypothesized that T2* measurement in the lung at 3 T MR system has a potential role to play as a method for assessment of pulmonary functional loss and disease severity in CTD patients. The purpose of this study was to determine the capability of pulmonary MRI with ultra-short TEs (UTEs) in a 3 T system for pulmonary functional and disease severity assessments in patients with CTD.