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Abstract #3967

T2* Measurements of 3 T MRI with Ultra-Short TE: Capability of Assessments for Pulmonary Functional Loss and Disease Severity in Patients with Connective Tissue Disease (CTD)

Yoshiharu Ohno1, 2, Mizuho Nishio1, Hisanobu Koyama1, 2, Masaya Takahashi3, Takeshi Yoshikawa1, Sumiaki Matsumoto1, Daisuke Takenaka1, Katsusuke Kyotani2

1Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 2Radiology, Kobe University Hospital, Kobe, Hyogo, Japan; 3Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; 4Philips Electronics Japan, Tokyo, Japan; 5Philips Healthcare Asia Pacific, Tokyo, Japan

CT is most widely used for radiological assessment of disease severity in CTDs. Recently, we have tried to determine the utility of regional T2* measurement in the lung for assessment of pulmonary diseases. We hypothesized that T2* measurement in the lung at 3 T MR system has a potential role to play as a method for assessment of pulmonary functional loss and disease severity in CTD patients. The purpose of this study was to determine the capability of pulmonary MRI with ultra-short TEs (UTEs) in a 3 T system for pulmonary functional and disease severity assessments in patients with CTD.