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Abstract #4018

Gd-EOB-DTPA in Patients with Primary Sclerosing Cholangitis (PSC) an Analysis of the Hepatobiliary Excretion Kinetic

Kristina Imeen Ringe1, Elmar Merkle2, Jan Hinrichs1, Frank Wacker1, Bernhard Meyer1

1Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Niedersachsen, Germany; 2Department of Radiology, Duke University Medical Center, United States

The purpose of this study was to analyze the hepatobiliary excretion of Gd-EOB-DTPA into different segments of the hepatobiliary system in 111 patients with primary sclerosing cholangitis (PSC) and to work out a possible correlation with severity of disease. The results of our study show, that hepatobiliary excretion in patients with PSC is significantly delayed compared to patients with normal liver function, and further dependent on bilirubin level, necessitating eventual adjustments of the MR imaging protocol.