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Abstract #4026

Clinicopathological Significance of the Peritumoral Decreased Uptake Area of Gd-EOB-DTPA in Hypervascular Hepatocellular Carcinoma: Novel Application of Gd-EOB-DTPA-Enhanced MRI

Akihiro Nishie1, Yoshiki Asayama1, Kousei Ishigami1, Daisuke Kakihara1, Tomohiro Nakayama1, Yasuhiro Ushijima1, Yukihisa Takayama1, Ken Shirabe1, Nobuhiro Fujita1

1Kyushu University, Fukuoka, Japan

For the first time we focused on the peritumoral decreased uptake area of Gd-EOB-DTPA (PDUAE) in HCC and investigated the significance of this pseudolesion by comparing variable clinical and pathological factors. As a result, PDUAE was associated with vascular invasion. When the presence of PDUAE was used as an indicator of vascular invasion, relatively high diagnostic performance was obtained. In addition, the vascular invasion of our enrolled cases was microscopic. In general, it remains difficult to detect microscopic vascular invasion on dynamic CT or MRI. Our results suggested that microscopic vascular invasion could be predicted with Gd-EOB-DTPA-enhanced MRI with ease.