Abstract #4028

MR Imaging Characterization and Staging of Malignant Central Bile Duct Stenosis: Added Value of the Hepatocyte Specific Contrast Agent Gadoxetate Disodium

Kristina Imeen Ringe¹, Hueseyin Bektas², Bastian Ringe², Patrick Opherk¹, Angela Reichelt¹, Joachim Lotz³, Frank Wacker¹, Bernhard Meyer¹

¹Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Niedersachsen, Germany; ²Department of General-, Visceral- and Transplantation Surgery, Hannover Medical School, Hannover; ³Department of Diagnostic Radiology, University Hospital Gttingen, Gttingen

The purpose of this prospective study was to assess the added value of the hepatocyte specific contrast agent gadoxetate disodium for characterization and staging of tumors in patients with malignant central bile duct stenosis. Intraoperative findings were used as gold standard. The results of our study show, that the application of gadoxetate disodium improves assessment of tumor extension, which is necessary to define tumor resectability. In this context images acquired in the late hepatocyte phase proved most useful for exact tumor delineation.