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Abstract #4053

Non-Invasively Quantitative Measurements of Intrarenal R2' in Human Using an Asymmetric Spin Echo EPI Sequence

Xiaodong Zhang1, Yudong Zhang2, Xuedong Yang2, Xiaoying Wang, 12, Hongyu An3, Jue Zhang1, 4, Jing Fang1, 4

1Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China; 2Dept. of Radiology, Peking University First Hospital, Beijing, China; 3Department of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; 4College of Engineering, Peking University, Beijing, China

Renal R2 provides critically important information to assess the renal oxygen metabolism in both normal and disease states. An asymmetric spin echo (ASE) single shot echo planar imaging (EPI) sequence can provide rapid measurements of R2 in human kidney. In addition, the proposed ASE R2measurement is highly reproducible and is sensitive to renal oxygenation changes under pharmacological conditions.