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Abstract #4086

Synthesis and Properties of Gadolinium Iodate Nanoparticles as a MRI/CT Contrast Agnet

Ja Young Park1, Krishna Kattel1, Wenlong Xu1, Badrul Alam Bony1, Woo Choul Heo1, Tirusew Tegafaw Mengesha1, Gang Ho Lee1

1Department of Chemistry, Kyungpook National University, Daegu, Korea, Republic of

The present work deals with bimodal imaging agent which emerges as new and efficient imaging techniques in clinical applications. D-glucuronic acid surface-coated ultra-small gadolinium iodate nanoparticles have been synthesized and well characterized. It may be used for both MRI contrast agent and CT contrast agent. Finally, we took in vivo T1 MR images and CT images of a rat with a brain tumor by using D-glucuronic acid coated ultrasmall gadolinium iodate nanoparticles. We observed a clear contrast enhancement in MR images and CT images of the tumor after injection of nanocolloid.