Abstract #4118

Motion Correction of Diffusion-Weighted Imaging of the Liver: Use of Velocity-Compensated Diffusion Gradients Combined with Tetrahedral Gradients

Masanori Ozaki¹,², Yusuke Inoue³, Tosiaki Miyati², Hirofumi Hata⁴, Shinya Mizukami⁵, Shotaro Komi⁴, Keiji Matsunaga³, Reiko Woodhams³, Shinichi Kan³

¹School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, Japan; ²Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa, Japan; ³Department of Diagnostic Radiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; ⁴Department of Radiology, Kitasato University Hospital, Kanagawa, Japan; ⁵Department of Radiology, Kitasato University Hospital, Sagamihara, Kanagawa, Japan

In diffusion-weighted imaging (DWI), the artificial elevation of the apparent diffusion coefficient (ADC) of the liver parenchyma occurs due to signal loss caused by cardiac motion. This effect can be reduced by using a velocity-compensated (VC) -DWI sequence. However, a limitation of the VC-DWI sequence is that it provides a lower SNR than a conventional DWI sequence. Tetrahedral gradients can be used to obtain higher SNRs than conventional orthogonal gradients. The purpose of our study was to evaluate the efficacy of a VC-DWI sequence combined with tetrahedral gradients (t-VC-DWI) in liver parenchyma.