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Abstract #4118

Motion Correction of Diffusion-Weighted Imaging of the Liver: Use of Velocity-Compensated Diffusion Gradients Combined with Tetrahedral Gradients

Masanori Ozaki1, 2, Yusuke Inoue3, Tosiaki Miyati2, Hirofumi Hata4, Shinya Mizukami5, Shotaro Komi4, Keiji Matsunaga3, Reiko Woodhams3, Shinichi Kan3

1School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, Japan; 2Graduate School of Medical Science, Kanazawa University, Kanazawa, Ishikawa, Japan; 3Department of Diagnostic Radiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; 4Department of Radiology, Kitasato University Hospital, Kanagawa, Japan; 5Department of Radiology, Kitasato University Hospital, Sagamihara, Kanagawa, Japan

In diffusion-weighted imaging (DWI), the artificial elevation of the apparent diffusion coefficient (ADC) of the liver parenchyma occurs due to signal loss caused by cardiac motion. This effect can be reduced by using a velocity-compensated (VC) -DWI sequence. However, a limitation of the VC-DWI sequence is that it provides a lower SNR than a conventional DWI sequence. Tetrahedral gradients can be used to obtain higher SNRs than conventional orthogonal gradients. The purpose of our study was to evaluate the efficacy of a VC-DWI sequence combined with tetrahedral gradients (t-VC-DWI) in liver parenchyma.