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Abstract #4143

IVIM Assessment of the Placenta, Basal Plate and Chorionic Plate in Diabetic Pregnancies

Devasuda Anblagan1, Ruta Deshpande2, Nia W. Jones2, Carolyn Costigan1, Caroline Wright3, David M. Morris4, 5, Nick Raine Fenning6, Lopa Leach7, George Bugg<s

1Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Nottingham University Hospitals NHS Trust, United Kingdom; 3Maternal and Fetal Health Research Group, University of Manchester, Manchester, United Kingdom; 4Imaging Sciences, University of Manchester, Manchester, United Kingdom; 5Biomedical Imaging Institute, University of Manchester, Manchester, United Kingdom; 6School of Clinical Sciences, University of Nottingham, United Kingdom; 7School of Biomedical Sciences, University of Nottingham, United Kingdom


High volume, low resistance placental blood flow (f) is essential for optimal nutrient exchange. Aberrant placental blood flow is associated with conditions such as maternal diabetes, often resulting in areas with abnormal vascular development. This study is the first report of measurements of IVIM in the chorionic plate. The results show no change in f with gestational age, (consistent with previous results in basal plate and placenta). No significant changes were found in diabetes.

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