L. Keith1, C. Francois2, M. Schiebler2, S. Reeder2, 3, F. Korosec1, 2
1Medical Physics, University of Wisconsin - Madison, Madison, WI, United States; 2Radiology, University of Wisconsin - Madison, Madison, WI, United States; 3Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States
We have previously introduced a method for acquisition of time-resolved contrast-enhanced MR angiography of the peripheral vasculature using fractional doses of contrast material (<0.1 mmol/kg). Undersampled 3D radial k-space trajectories (VIPR) and HYPR image processing are combined to provide distal time-resolved MRA with high spatial and temporal resolution while maintaining good image quality with contrast material injections as little as 0.025 mmol/kg in patients with known PVD. Using this method, it is possible to decease the dose of gadolinium-based contrast agents for time-resolved, contrast-enhanced peripheral MRA while maintaining high image quality and diagnostic confidence.