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Abstract #4187

Chemical Exchange Sensitive Imaging Without a Long Irradiation Pulse: Irradiation with Toggling Inversion Preparation

Tao Jin1, Seong-Gi Kim1

1Department of Radiology, University of Pittsburgh, Pittsburgh, PA, United States

One practical issue for the chemical exchange (CE) based MRI techniques is that the conventional T1 and T2 relaxations often contaminate the CE imaging contrast. Another issue is that due to hardware or specific absorption rate limitations, CE-sensitive image often has to be acquired using a short irradiation pulse, although a long pulse reaching the steady state may simplify the quantification and sometimes results in better image contrast. Here we propose a novel acquisition method that can use a relatively short irradiation pulse to remove T1 and T2 effects in the CE contrasts, and also to obtain the steady-state imaging contrast.