Free-Breathing Dynamic Contrast-Enhanced MRI of the Liver with Radial Golden-Angle Sampling Scheme and Advanced Compressed-Sensing Reconstruction.

Hersh Chandarana¹, Li Feng¹, Tobias Kai Block¹, Andrew B. Rosenkrantz¹, Ruth P. Lim¹, Dewey Chu¹, Daniel K. Sodickson¹, Ricardo Otazo¹

Dynamic post-contrast liver MR examination is performed with Cartesian k-space sampling in a breath-hold (BH). However, this results in non-diagnostic images in patients who cannot adequately breath-hold. Purpose of this study was to compare image quality of free-breathing radial (interleaved angle-bisection and golden angle) acquisition schemes reconstructed with either view sharing (KWIC) or joint compressed-sensing and parallel imaging reconstruction (CS-PI), to conventional BH exam. Our results demonstrate that free-breathing radial golden angle trajectory continuous acquisition scheme with CS-PI reconstruction has image quality comparable to a breath-hold exam and significantly better than interleaved radial acquisition with KWIC or CS-PI reconstruction.