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Abstract #4222

Investigation of Spatial and Temporal Fidelity of HYPR Processing Using a Motion Phantom

L. Keith1, M. Rahimi2, J. Holmes3, K. Wang3, J. Brittain3, F. Korosec1, 4

1Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 2Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States; 3Global Applied Science Laboratory, GE Healthcare; 4Radiology, University of Wisconsin - Madison, Madison, WI, United States


In this work, an experimental setup has been designed in which a computer-controlled motion stage is used to translate an object through the imaging FOV during data acquisition in an attempt to mimic a bolus of contrast material traveling through vasculature. Since the motion is computer controlled and the dynamic elements of the phantom are well-defined with sharp edges, the input to the HYPR process is well-known. We conduct two experiments: Experiment 1 investigates the temporal and spatial fidelity of HYPR processing; Experiment 2 compares the fidelity of HYPR against that of current clinical MRA techniques.