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Abstract #4272

Fast Mapping of Absolute Water Content in the Human Brain Using TAPIR

Klaus H. M. Mllenhoff1, 2, Fabian Keil1, Zaheer Abbas1, Vincent Gras1, Miriam Rabea Kubach1, Ana-Maria Oros-Peusquens1, N. Jon Shah1, 3

1Institute of Neuroscience and Medicine - 4, Forschungszentrum Jlich, Jlich, Germany; 2Department of Cognitive Neuroscience, University Maastricht, Maastricht, Netherlands; 3JARA - Faculty of Medicine, RWTH Aachen University, Aachen, Germany

Absolute water content in the human brain is highly regulated and shown to change in various diseases.Thus mapping of H2O values in clinical acceptable measurement times is of great interest. Here we present a fast and accurate method for mapping H2O values in vivo based on the 2D TAPIR approach.