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Abstract #4282

Cortical Layers One by One: T2*, Phase and Susceptibility at 80μm Resolution

Ana-Maria Oros-Peusquens1, Johannes Lindemeyer1, Alard Roebroeck2, Ralf A.W. Galuske3, Hansjuergen Bratzke4, N. Jon Shah1

1INM-4, Research Centre Juelich, Juelich, Germany; 2Dept. of Psychology, University of Maastricht, Netherlands; 3Dept. of Biology, TU Darmstadt, Germany; 4Dept. of Forensic Medicine, Faculty of Medicine, JWG-University, Frankfurt/M, Germany

We report on a multiparametric, high-resolution study of the motor cortex at 9.4T. Two intracortical bands were visualised, with contrast strikingly different from that of the surrounding cortex. We observe orientation dependence of the contrast in both magnitude and phase images as well as T2* and susceptibility maps. Interestingly, the dependence of the visualisation of the cortical bands on direction is complementary in magnitude and phase. This is an indication of microstructure dependence of T2* and phase contrast.