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Abstract #4285

Towards Interactive Super-Resolution Reconstruction of Whole-Body MRI Mouse Data

Artem Khmelinskii1, Esben Plenge2, Peter Kok3, 4, Dirk Poot2, Oleh Dzyubachyk3, Charl P. Botha4, Ernst Suidgeest5, Wiro Niessen2, 6, Louise van der

1Division of Image Processing, Dept. of Radiology, LUMC, Leiden, The Netherlands, Leiden, Zuid-Holland, Netherlands; 2BIGR, Depts. of Radiology and Medical Informatics, ErasmusMC, Rotterdam, Netherlands; 3Division of Image Processing, Dept. of Radiology, LUMC, Leiden, Netherlands; 4Data Visualization Group, Dept. of Mediamatics, TU Delft, Netherlands; 5Dept. of Radiology, Molecular Imaging Laboratories Leiden, Section Nuclear Medicine, LUMC, Leiden, Netherlands; 6Quantitative Imaging Group, Dept. of Imaging Science & Technology, TU Delft, Netherlands; 7Depts. of Anatomy & Embryology, LUMC, Leiden, Netherlands

We present a new approach for producing highly resolved, localized isotropic volumes-of-interest in whole-body mouse MRI. This enables interactive HR visualization and exploration of anatomical structures in MRI. The idea is similar to that of well-known web-based geographical maps, where it is possible from a global overview image to zoom in on a detail of interest. Such functionality is relevant in a biomedical setting when working with high-resolution volumetric data. Using the method presented in this paper, from a global LR image the user can interactively zoom in on a sub-volume of interest.