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Abstract #4339

Synthesis, Characterization, In Vitro and in vivo MR Studies of Dy(OH) 3 Nanostructures for T2 MRI Contrast Agent

Krishna Kattel1, Ja Young Park1, Wenlong Xu1, Badrul Alam Bony1, Woo Choul Heo1, Tirusew Tegafaw Mengesha1, Gang Ho Lee1

1Department of Chemistry, Kyungpook National University, Daegu, Korea, Republic of

Dy-compounds are promising candidates for MRI contrast agent. Dy3+ has the shortest electronic relaxation time and highest magnetic moment (10.6 B) which induce water proton relaxation that primarily affect T2. It increases significantly with the external magnetic field, and is proportional to the square of the magnetic moment of the Dy3+ ion. Dy(OH) 3 nanostructures were examined for their possible use in MR imaging and tracking of cells by investigating their cytotoxic behaviors.