Meeting Banner
Abstract #4377

Temporally Flexible Tracking of Neuro-Progenitor Stem Cells Using Golden Angle Incremented Linear Combination Steady-State Free Procession (LCSSFP) Imaging for Artifact Reduction.

H. Douglas Morris1, J. Andrew Derbyshire2

1NIH Mouse Imaging Facility, National Institutes of Health, Bethesda, MD, United States; 2Laboratory for Cardiac Energetics, National Institues of Health, Bethesda, MD, United States

Rapid individual cell tracking of endogenously labeled stem cells is shown using high-field MRI and balanced Steady-State Free Procession sequences. We present a field artifact suppression technique based on the Golden Angle progression for the RF phase cycle as a modification to Linear Combination SSFP (LCSSFP). The use of golden-angle LCSSFP yields a temporally flexible acquisition scheme that can yield continuous progression of resulting images that do not overlap in pulse-band artifacts. This resulting method can yield very high resolution images quickly with few global artifacts while still tracking magnetic particles.