Abstract #4385

Kinetic Modelling of 13C Hyperpolarised Pyruvate Metabolism Using Measured Arterial Input Function in Tumours

Samira Kazan¹, Steven Reynolds², Jo Bluff¹, Aneurin Kennerley³, Emily Wholey⁴, Jason Berwick³, Vincent Cunningham⁵, Martyn Paley², Gillian Tozer¹

¹Oncology, University of Sheffield, Sheffield, United Kingdom; ²Human Metabolism, University of Sheffield, United Kingdom; ³Psychology, University of Sheffield, Sheffield, United Kingdom; ⁴Institute of Cancer Research, London, United Kingdom; ⁵Aberdeen Biomedical Imaging Centre, University of Aberdeen, Scotland, United Kingdom