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Abstract #0041

Resting-State fMRI at 4 Hz

Ying-Hua Chu1, Jyrki Ahveninen2, Tommi Raij2, Wen-Jui Kuo3, John W. Belliveau2, Fa-Hsuan Lin1

1Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; 2A. A. Martinos Center, Massachusetts General Hospital, Charlestown, MA, United States; 3Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan

Resting-state fMRI studies reflecting functional connectivity have been typically limited to frequencies below 0.1 H. Here, we hypothesize that fMRI can detect interregional correlations in MRI time series at frequencies above 0.1 Hz as well. Using MR inverse imaging (InI) at a 10 Hz sampling rate, we studied interhemispheric correlations between primary sensorimotor and visual cortices. We found significant correlations at 4 Hz (average Z-score ~8) that were about 60% of those observed at 0.1 Hz.