New Insights in the Disagreement of Transvalvular Mean Pressure Gradient Measured by Transthoracic Echo-Doppler and Cardiovascular Magnetic Resonance in Patients with Aortic Stenosis

Julio Garcia¹, Romain Capoulade², Lyes Kadem³, Eric Larose², Philippe Pibarot²

Transvalvular mean pressure gradient (MPG) measured by CMR often underestimates echo-Doppler MPG. This underestimation might be due to physical factors as flow turbulence generated downstream the severe AS, local signal loss, background noise and phase wrap. However fluid dynamic parameters may play also a significant role in the MPG measurement by CMR. The aims of this study were to identify the fluid dynamic factors associated with MPG underestimation by CMR and to investigate the association of those factors in the AS severity assessment by CMR.