Abstract #0105

Time Efficient Determination of Spin Compartments by Time Encoded Arterial Spin Labeling

Sophie Schmid¹, Wouter M. Teeuwisse¹, Eidrees Ghariq¹, Andrew Webb¹, Hanzhang Lu², Matthias J.P. van Osch¹

¹C.J.Gorter Center for High Field Magnetic Resonance, Radiology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands; ²UT Southwestern Medical Center, Dallas, TX, United States

The aim of this study is to employ a method to measure the transverse relaxation time as a function of the inflow time and to distinguish spin compartments based on their T2 in a highly time-efficient and voxelwise manner. By the use of Time encoded (also known as Hadamar encoded) pseudo Continuous Arterial Spin Labeling (te-pCASL) in combination with T2-Relaxation-Under-Spin-Tagging (TRUST) it is feasible to be more specific due to the short bolus duration and reduce the measurement time, while still keeping an equal SNR compared to separate multi-timepoint pCASL scans.