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Abstract #0105

Time Efficient Determination of Spin Compartments by Time Encoded Arterial Spin Labeling

Sophie Schmid1, Wouter M. Teeuwisse1, Eidrees Ghariq1, Andrew Webb1, Hanzhang Lu2, Matthias J.P. van Osch1

1C.J.Gorter Center for High Field Magnetic Resonance, Radiology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands; 2UT Southwestern Medical Center, Dallas, TX, United States

The aim of this study is to employ a method to measure the transverse relaxation time as a function of the inflow time and to distinguish spin compartments based on their T2 in a highly time-efficient and voxelwise manner. By the use of Time encoded (also known as Hadamar encoded) pseudo Continuous Arterial Spin Labeling (te-pCASL) in combination with T2-Relaxation-Under-Spin-Tagging (TRUST) it is feasible to be more specific due to the short bolus duration and reduce the measurement time, while still keeping an equal SNR compared to separate multi-timepoint pCASL scans.