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Abstract #0140

Magnetic Particle Imaging for Safe Angiography and Stem Cell Tracking

Emine U. Saritas1, Patrick W. Goodwill1, Justin J. Konkle1, Laura R. Croft1, Kuan Lu1, Bo Zheng1, Steven M. Conolly1, 2

1Department of Bioengineering, University of California, Berkeley, Berkeley, CA, United States; 2Department of Electrical Engineering and Computer Sciences,, University of California, Berkeley, Berkeley, CA, United States

Magnetic Particle Imaging (MPI) is a new imaging modality that re-uses FDA-approved superparamagnetic iron oxide (SPIO) nanoparticle contrast agents in a new imaging scanner (i.e., not an MRI scanner) [1-3]. The MPI method has ideal SNR, penetration, linearity and contrast, and is completely non-invasive. Moreover, compared to iodine and gadolinium, the SPIO contrast agents are much safer for patients with Chronic Kidney Disease (CKD). This work describes our state-of-the-art MPI scanners and MPIs potential for applications such as angiography and quantitative cell tracking.