Flow Compensated Quantitative Susceptibility Mapping for Venous Oxygenation Imaging

Bo Xu¹, ², Tian Liu², Pascal Spincemaille², Yi Wang¹, ²

Flow artifacts in quantitative susceptibility mapping (QSM) are corrected with a fully flow compensated multi-echo gradient echo sequence combined with a hybrid linear-quadratic fitting of the phase data. Phantom experiments and in vivo studies demonstrate improvements in the estimation of the field inhomogeneity and the susceptibility map. This enables more reliable venous oxygenation quantification in the brain with QSM.