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Abstract #0230

in vivo Validation of T2-Based MR Thermometry in Adipose Tissue Layers for HIFU Near-Field Monitoring

Paul Baron1, Mario Ries1, Martijn de Greef1, Roel Deckers1, Max Khler2, Jukka Tanttu2, Chrit T.W. Moonen1, Lambertus W. Bartels1

1Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands; 2Philips Healthcare, Vantaa, Finland

The feasibility of using T2 mapping for monitoring the near field temperature in subcutaneous adipose tissue was investigated during a HIFU liver ablation in an in vivo porcine model. Calibrations showed that T2 changed linearly and reversible with temperature. When compared to the fiber optic probe the accuracy was better than 0.9C. During the in vivo porcine liver sonication and the subsequent cool-down period T2-thermometry allowed observing the temperature change due to near-field heating in the adipose tissue with a thermometric precision of 1.1C.