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Abstract #0232

Towards Improving Predictive Capabilities of MR-ARFI for Transcranial Focused Ultrasound Therapy

Elena Kaye1, Yoni Herzberg2, Gil Navon3, Kim R. Butts Pauly1

1Radiology, Stanford University, Palo Alto, CA, United States; 2School of Physics and Astronomy, Tel Aviv University, Tel Aviv, Israel; 3School of Chemistry, Tel Aviv University, Tel Aviv, Israel

MR-guided acoustic radiation force imaging (MR-ARFI) has been recently proposed to drive adaptive phase-aberration correction for transcranial ultrasound therapy. MR-ARFI detects displacement of tissue caused by acoustic radiation force in the direction of encoding. In a hemispherical transducer, component of the force emitted by the elements along the main axis varies based on geometric position of the element, therefore encoding in this direction is less sensitive to the ultrasound emission and phase aberrations of the peripheral elements.