Abstract #0247

Multi-Echo Acquisition of 3D TOF and SWI of Radiation-Induced Cerebral Microbleeds at 7T

Wei Bian¹,², Suchandrima Banerjee³, Douglas A.C. Kelly⁴, Susan M. Chang⁵, Sarah J. Nelson¹,², Janine M. Lupo²

¹Graduate Program in Bioengineering, University of California San Francisco & Berkeley, San Francisco, CA, United States; ²Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States; ³Global Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; ⁴Global Applied Science Laboratory, GE Healthcare, San Francisco, CA, United States; ⁵Neurological Surgery, University of California San Francisco, San Francisco, CA, United States

We designed a multi-echo sequence for the simultaneous acquisition of 3D TOF and SWI images at 7T for depicting radiation-induced cerebral microbleeds, intracranial arteries, and veins in one acquisition. The first echo was used to create TOF images of arteries, while those from the remaining three were combined to reconstruct SWI images for visualization of microbleeds and veins. Experimental results from a volunteer and two patients showed that the images acquired from the multi-echo sequence achieved a level of quality comparable to that of each obtained with a single-echo sequence.