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Abstract #0297

Regional Structural Differences Across Functionally Parcellated Brodmann Areas of Human Primary Somatosensory Cortex

Rosa M. Sanchez Panchuelo1, Julien Besle2, Olivier E. Mougin1, Penelope A. Gowland3, Richard W. Bowtell3, Denis Schluppeck2, Susan T. Francis3

1Sir Peter Mansfield Magnetic Resonance Centre , University of Nottingham, Nottingham, United Kingdom; 2School of Psychology, University of Nottingham, Nottingham, United Kingdom; 3Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, United Kingdom

We exploit the improved BOLD CNR and high spatial resolution achievable at 7T to study the correlation of structure and function within the primary somatosensory cortex (S1). Using a travelling wave fMRI paradigm to map the within-digit representation of the index, middle, and ring fingers in S1, we identify multiple map reversals at the tip and base, corresponding to the boundaries between Brodmann areas 3a/3b/1/2. Based on high resolution structural MRI data, we inspect these functionally-parcellated Brodmann areas for differences in cortical thickness and MR measures (MTR and signal intensity in PSIR images) that are sensitive to myelination.