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Abstract #0311

Motion Robust High Resolution FLASH

Onur Afacan1, Ali Gholipour1, Erez Nevo2, Simon K. Warfield1

1Computational Radiology Laboratory, Department of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States; 2Robin Medical, Inc, Baltimore, MD, United States

In this work we propose a novel motion robust high-resolution FLASH acquisition scheme to be used for cortical lesion detection in uncooperative subjects. This scheme is based on acquiring multiple low-resolution images with different orientations and then combining these acquisitions into an isotropic high-resolution image using super-resolution reconstruction. We use a motion sensor to identify the low-resolution images corrupted with motion to reacquire them, as well as to correct for the motion between the low-resolution acquisitions. With this method whole brain images with isotropic resolution of 0.6 mm were reconstructed with a total scan time of 20 minutes.