Abstract #0316

Quantitative Spiral Perfusion Imaging: Initial Clinical Experience

Michael Salerno¹,², Yang Yang³, Sujith Kuruvilla¹, Craig H. Meyer³, Christopher M. Kramer,¹²

¹Medicine, Cardiology, University of Virginia, Charlottesville, VA, United States; ²Department of Radiology, University of Virginia, Charlottesville, VA, United States; ³Biomedical Engineering, University of Virginia, Charlottesville, VA, United States

We present our initial clinical experience using a newly developed quantitative spiral perfusion pulse sequence for adenosine stress CMR in patients with coronary artery disease. High resolution perfusion images and pixel-wise maps of absolute myocardial perfusion can be obtained with this pulse sequence without any time penalty during data acquisition. In normal subjects the resting perfusion is near 1mL/g/min as expected. In two patients who underwent cardiac catheterization there was excellent correlation between regions of reduced stress perfusion and obstructive coronary artery disease..