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Abstract #0320

First-Pass Contrast-Enhanced Cardiac Perfusion with 3D Coverage Per Heartbeat with 3D Through-Time Radial GRAPPA

Kestutis Barkauskas1, Jesse Hamilton1, Bruce S. Spottiswoode2, Sven Zuehlsdorff2, Mark A. Griswold1, 3, Nicole Seiberlich1

1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 2Cardiovascular MR R&D, Siemens Medical Solutions, Chicago, IL, United States; 3Radiology, Case Western Reserve University, Cleveland, OH, United States

The objective was to provide whole-heart coverage within diastole of each cardiac cycle during a first-pass contrast-enhanced cardiac perfusion study. An ECG-gated, 3D Radial FLASH sequence with a stack-of-stars trajectory required 341ms per volume by undersampling the angular and partition directions. Cartesian GRAPPA in the partition direction followed by 3D Through-time Radial GRAPPA in the angular direction reconstructed the data. Despite net 16-fold acceleration with respect to a Cartesian trajectory, partition alias was not observed and myocardial uptake followed expected dynamics. These results suggest that 3D Through-time Radial GRAPPA may be a viable option for obtaining clinically relevant cardiac perfusion estimates.