Volumetric Measurement of Human Brain T1 in vivo Using Pulsed Pseudo Random Amplitude Modulation

Xiaowei Zou¹, ², Truman R. Brown²

This work presents a novel method named pulsed Pseudo Random Amplitude Modulation (PRAM)for T1 measurement, and validates it on T1 phantoms. Both phantom and human results confirm that this method agrees well with the conventional inversion recovery method. Without fast imaging acceleration, the scan time per slice (128x128 matrix size) on human brain is 1.5s.