Meeting Banner
Abstract #0525

Retinotopic-Specific Changes of Cerebral Blood Flow and Grey Matter in Visual Cortex of Patients with Glaucoma

Bo Wang1, Shaodan Zhang2, 3, Y Xie2, Ningli Wang2, Chun Zhang3, Xiaohong Joe Zhou4, Yan Zhuo1

1State Key Lab of Brain & Cognitive Science, Institute of Biophysics, Chinese Academy of China, Beijing, China; 2Beijing Tongren Hospital affiliated to Capital Medical University, Beijing, China; 3Peking University Third Hospital, Beijing, China; 4University of Illinois Medical Center at Chicago, Chicago, IL, United States

Differences were observed in blood flow, morphology and metabolites in the visual cortex between POAG (patients with primary open angle glaucoma) patients and age-matched normal controls, suggesting that rCBF and/or VBM may be used as a specific and sensitive marker in assessing brain injury in glaucoma patients.