Time-Resolved Non-Contrast Enhanced 4-D Dynamic MRA Using Multi-Bolus TrueFISP Based Spin Tagging with Alternating Radiofrequency (True-STAR)

Lirong Yan¹, Noriko Salamon², Danny J.J. Wang¹

The purpose of this study is to introduce a new non-contrast dynamic MRA (dMRA) technique termed multi-bolus TrueSTAR, by combining the benefits of pulsed ASL, including short RF duration and low SAR, and pseudo-continuous ASL (pCASL), including higher SNR and prolonged labeling bolus. Multi-bolus dMRA offered a prolonged tagging bolus compared to the standard single-bolus dMRA, and allowed improved visualization of the draining veins in arteriovenous malformation. Compared to pCASL based dMRA, multi-bolus dMRA provided visualization of the full passage of the labeled blood with the flexibility for both static and dynamic MRA.