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Abstract #0627

Natural Course of Intracranial Vessel Wall Lesions in Stroke- And TIA Patients at 7.0 Tesla MRI

Anja G. van der Kolk1, Jaco J.M. Zwanenburg1, Manon Brundel2, Geert Jan Biessels2, Fredy Visser1, 3, Peter R. Luijten1, Jeroen Hendrikse1

1Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands; 2Department of Neurology, University Medical Center Utrecht, Utrecht, Netherlands; 3Philips Healthcare, Best, Netherlands

A substantial percentage of patients with cerebrovascular disease have been shown to have intracranial vessel wall lesions. It is, however, not clear whether these are stable lesions, or changing over time. To assess the natural course of these lesions, 35 ischemic stroke- or TIA-patients with an Magnetization Preparation Inversion Recovery (MPIR)-TSE scan at 7.0 Tesla within 1 week and 1 month after the ischemic event were included. The majority of patients had stable lesions, indicating a prolonged cerebral atherosclerotic process. The used MPIR-TSE vessel wall sequence at 7.0 Tesla may allow for assessment over time of (progressive) intracranial atherosclerotic plaques.