Oxygen Enhanced Lung MRI by Simultaneous Measurement of T1 and T2* During Free Breathing

Simon Triphan¹, ², Felix A. Breuer¹, Hans-Ulrich Kauczor², Peter M. Jakob¹, ³

While both T₁ and T₂* are reduced in hyperoxic conditions, these changes reflect different aspects of lung function. A method for measuring both parameters simultaneously using a inversion recovery multi-gradient echo experiment is proposed. By applying an asymmetric radial readout with a golden angle distribution, lung signal is maximised while enabling self-gating to compensate for breathing motion. Since the dc-signal is distorted by the inversion recovery, a correction to recover an undisturbed signal is shown. Generating self-gated parameter maps provides co-registration for T₁ and T₂* maps as well as for maps acquired under different oxygenation conditions.