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Abstract #0679

A New Validated MRI Method for Measuring Colonic Transit Time

Gemma Louise Chaddock1

1Physics & Astronomy, The University of Nottingham, Nottingham, Nottinghamshire, United Kingdom


We developed a novel MRI technique to measure colonic transit time using MRI marker capsules. We validated this new method against the gold standard X-ray radiopaque markers. 20 subjects took part in the study twice (test-retest). On each study week they swallowed 5 MRI transit marker capsules 24 hours before undergoing an MRI scan. Subjects also undertook the X-ray test, swallowing 20 radiopaque markers on 3 consecutive days with a single abdominal x-ray taken on day 4 as validated in the literature. We found that the MRI transit marker and radiopaque marker results correlated well (Spearmans r= 0.85, p<0.0001).This could provide an alternative test for measuring colonic transit which is simple to carry out and interpret, convenient, non invasive, and does not involve exposure to ionising radiation.

Keywords

colontransitpillssubjectscapsulescorrelationcoilgoodmarkerspositionbodyexampleexcellentgadoliniummarkermeasuringpillscoreassessbowelcontrastdependingexposehoursinvasivepatientradiationreceivereproducibilitysimpleswallowedtransversevalidatedvisitsadditionagedagentallowingalteredalternativeappliedapproved