Common Features in the Orientation Dependence of MR Diffusion, Susceptibility and Relaxation Measurements in the Human Brain in vivo: Constrained Susceptibility Anisotropy Estimation

Cynthia Wisnieff¹, Pascal Spincemaille², Yi Wang¹

In this work we examine the similarities between the orientation dependent nature of diffusion, magnetic susceptibility and relaxation rate. It is found that highly structured areas, such as the white matter, have the most common structural information in these orientation dependent processes consistent with the known structure and magnetization of white matter. In the estimation of susceptibility anisotropy was found that, when either diffusion and relaxation rate tensor information was used in the constrained susceptibility tensor reconstruction, similar estimates of magnetic susceptibility anisotropy could be obtained.