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Abstract #0711

in vivo Measurement of Conduction Velocity and Axon Diameter Properties in the Human Brain

Assaf Horowitz1, Daniel Barazany1, Ido Tavor1, Moran Berenstein1, Galit Yovel2, Yaniv Assaf1

1Neurobiology, Tel Aviv University, Tel Aviv, Israel, Israel; 2School of psychology, Tel Aviv University, Tel Aviv, Israel, Israel

Previous ex-vivo studies, performed on exited nerve, had shown that the Axonal Conduction Velocity (ACV) of myelinated fibres is proportional to its diameter (1). Recent studies have succeeded to measure the rat brain (2) and the human brain (3) axon diameter distribution (ADD) in-vivo, using AxCaliber - a diffusion MRI methodology (4). In this study we succeeded to show a correlation between human visual callosal fibers ADD to its ACV which was measured through EEG recording and behavioral tasks.