Abstract #0744

Comparison of Contrast-Enhanced Magnetic Resonance Perfusion Imaging and Magnetic Resonance Fourier Decomposition with Single-Photon Emission Computed Tomography as Clinical Reference Standard for Lung Perfusion in Patients with Suspected Chronic Thromboe

Marcel Gutberlet¹, Christian Schnfeld¹, Jan Hinrichs², Julius Renne¹, Georg Berding³, Marius Hoeper⁴, Tobias Welte⁴, Frank Bengel³, Frank Wacker¹, Jens Vogel-Claussen¹

¹Institute of Radiology, Medical School Hannover, Hannover, Lower Saxony, Germany; ²Institute of Radiology, Hannover Medical School, Hannover, Lower Saxony, Germany; ³Clinic for Nuclear Medicine, Medical School Hannover, Hannover, Lower Saxony, Germany; ⁴Clinic of Pneumology, Medical School Hannover, Hannover, Lower Saxony, Germany

Dynamic contrast-enhanced (DCE) MR perfusion imaging and perfusion-weighted (pw) MR Fourier decomposition (FD) are compared to single-photon emission computed tomography (SPECT) ventilation/ perfusion (V/Q) scan as clinical reference standard for lung perfusion in patients with suspected chronic thromboembolic pulmonary hypertension (CTEPH). The lung segments of 13 patients were scored as segmental, subsegmental or no perfusion defect for the evaluated methods. In all patients CTEPH was diagnosed by the three methods. The analysis provided a good agreement of DCE MR perfusion imaging compared to SPECT and a moderate agreement of FD compared to SPECT.