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Abstract #0801

Typical Patterns of Myelin Neurodevelopment and Cognitive Abilities in Babies and Toddlers

Jonathan O'Muircheartaigh1, 2, Douglas C. Dean III1, Holly Dirks1, Nicole Waskiewicz1, Katie Lehman1, Michelle Han1, Lindsay Walker1, Beth A. Jerskey1, Sean C. L. Deoni1

1Engineering, Brown University, Providence, RI, United States; 2Neuroimaging, King's College London, London, United Kingdom

The trajectory of myelination in the developing brain is coupled with progressive optimisation of cognitively relevant brain networks. Here we use a multivariate technique, independent component analysis, to parcellate quantitative myelin maps (mcDESPOT) from 200 children between 3 months and 5 years, into clusters with consistent developmental trajectories. We demonstrate distributed, functionally relevant, systems that myelinate concurrently.