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Abstract #0837

Detailed Laminar Characteristics of the Human Neocortex Revealed by NODDI

Michiel Kleinnijenhuis1, 2, Hui Zhang3, Dirk Wiedermann4, Benno Ksters5, Anne-Marie van Cappellen van Walsum1, 6, David G. Norris2, 6

1Department of Anatomy, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 2Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands; 3Department of Computer Science & Centre for Medical Image Computing, University College London, London, United Kingdom; 4Max Planck Institute for Neurological Research, Cologne, Germany; 5Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 6MIRA Institute for Biomedical Technology and Technical Medicine, Enschede, Netherlands


We demonstrate that, using the multi-compartment tissue model NODDI, a fine-grained description of the laminae of the human neocortex can be achieved outperforming diffusion tensor metrics.

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