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Abstract #0842

HARDI and Fiber Tractography at 1 Mm Isotropic Resolution

Sjoerd B. Vos1, Murat Aksoy2, Zhaoying Han2, Samantha J. Holdsworth2, Christoph Seeger2, Maclaren Julian2, Alexander Brost2, Alexander Leemans1, Roland Bammer2

1Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands; 2Center for Quantitative Neuroimaging, Department of Radiology, Stanford University, Stanford, CA, United States

By combining advanced 3D DW EPI acquisitions with high-angular resolution diffusion imaging we have created a unique DWI dataset, of 1mm true isotropic resolution with 60 diffusion weighted directions. This dataset was reconstructed to create subsets of low angular (15 and 30 directions) and lower spatial (2mm isotropic) resolution, to compare the influence of both of these factors on fiber tractography, both in a qualitative, visual, manner as well as quantitatively.