Abstract #0844

Baseline GABA Concentration More Strongly Predicts Baseline BOLD Signal Synchrony Than CBF in Visual Cortex

Swati Rane¹, Emily Mason², Subechhya Pradhan¹, Erin Hussey², Kevin Waddell¹, John C. Gore¹,³, Brandon Ally,²⁴, Manus J. Donahue¹,⁴

¹VUIIS, Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States; ²Neurology, Vanderbilt University, Nashville, TN, United States; ³Biomedical Engineering, Vanderbilt University, Nashville, TN, United States; ⁴Psychiatry, Vanderbilt University, Nashville, TN, United States

This study investigates the relationship between baseline BOLD synchrony and perfusion (CBF) and baseline GABA concentration in the visual cortex. BOLD synchrony at rest was more strongly correlated with baseline GABA levels than with absolute CBF.