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Abstract #0873

An Atlas of the Anatomy of Human Brain Viscoelasticity

Jing Guo1, Sebastian Hirsch2, Sebastian Papazoglou1, Andreas Fehlner3, Michael Scheel1, Jens Wuerfel4, Juergen Braun5, Ingolf Sack1

1Department of Radiology, Charite - University Medicine Berlin, Berlin, Germany; 2Department of Radiology, Charit - Universittsmedizin Berlin, Berlin, Germany; 3Department of Radiology, Charit University Medicine, Berlin, Germany; 4Institute of Neuroradiology, University Luebeck, Luebeck, Schleswig-Holstein, Germany; 5Department of Medical Informatics, Charite - University Medicine Berlin, Berlin, Germany

We introduce a novel wave field reconstruction method which we used for analyzing 3D-multifrequency MRE brain data of 23 healthy volunteers providing viscoelastic parameter maps with a spatial resolution superior to former approaches. Individual parameter maps reflecting the magnitude of the complex modulus and the powerlaw exponent of the springpot model were normalized and averaged in order to obtain an atlas of the mechanical anatomy of the human brain.