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Abstract #0886

Three-Dimensional Maximum Probabilistic Cerebellar Atlas of Young Children

Priya lakshmi Narayanan1, 2, Jesuchristopher Joseph1, 2, Chirstopher Warton1, Chirstopher D. Molteno3, Joseph L. Jacobson, 14, Sandra W. Jacobson, 14, Ernesta M. Meintjes1, 2

1University of Cape Town, Cape Town, Western Cape, South Africa; 2MRC/UCT Medical Imaging Research Unit, Cape Town, Western Cape, South Africa; 3Department of Psychiatry, University of Cape Town, Cape Town, Western Cape, South Africa; 4Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United States

Brain atlases serves as a map of spatial arrangement of anatomical structures. Cerebellum is functionally heterogeneous by the fact that it is connected to cerebrum and spinal cord and occupies only 10-20% of the brain and contains half the number of neurons. In this study, we have registered the cerebellum from different subjects to the common age appropriate template and generated a probabilistic atlas which is known to encode the anatomic variability present in the cerebellum of our subjects. We propose to create cerebellar parcellations automatically and highlight on translating macroscopic structures of the cerebellum obtained from the manual delineations.