Abstract #0916

A Comparative Study of Dynamic Susceptibility Contrast and Arterial Spin Labeling in Childhood Brain Tumours.

Rishma Vidyasagar¹, Laura M. Parkes¹, Shivaram Avula², Barry Pizer², Laurence Abernethy²

¹Biomedical Imaging Institute, School of Population Health, University of Manchester, Manchester, Greater Manchester, United Kingdom; ²Alder Hey Children's Hospital, Liverpool, Merseyside, United Kingdom

DSC is a common technique used to ascertain measures of cerebral blood flow in a clinical setup. It is however an invasive technique and often restricts repeatable measures in an individual. The Look-Locker ASL sequence provides a non-invasive means of obtaining different measures of perfusion within the human brain at multiple timepoints. In this study we compare measures derived from DSC and ASL to investigate the feasibility of using a non-invasive ASL technique on patients with brain tumours.