Abstract #1150

Assessment of a Continuous Multi-Compartmental Intra-Voxel Incoherent Motion (IVIM) Model for the Human Brain

Burkhard Mdler¹, Dariusch Reza Hadizadeh²,³, Jrgen Gieseke²,⁴

¹Neurosurgery, University Bonn - Medical Centre, Bonn, Germany; ²Radiology, University Bonn - Medical Centre, Bonn, Germany; ³Neuroradiology, University Bonn - Medical Centre, Bonn, Germany; ⁴Philips Healthcare, Best, Netherlands

Several studies have utilized IVIM for various clinical applications in the abdomen as well as for animal experiments. However, studies in the human brain are rare and without further consensus about its clinical value, application and comparison to conventional perfusion techniques possibly due to the complex diffusion properties in the nervous system and the inherent low SNR.