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Abstract #1236

T2* Measurement of the Pituitary with Susceptibility Artifact Compensation at 3T

Yoonho Nam1, Eung Yeop Kim2, Dong-Hyun Kim1

1School of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea; 2Department of Radiology, University Hospital, Cincinnati, OH, United States

Preclinical diagnosis of iron overload in the pituitary gland is important for chronically transfused patients with hemoglobinopathies such as thalassemia.1,2 T2* measurement is very sensitive for detecting iron deposition in several tissues3 but severe susceptibility artifact (due to sphenoid sinus) makes T2* measurement in the pituitary gland difficult. Instead, T2 measurement or T2*-weighted imaging have been used to assess iron deposition in the pituitary gland.1,2 In this study, we propose a T2* measurement method based on field map analysis and susceptibility artifact correction in the pituitary gland ultimately aimed at evaluating iron overload.