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Abstract #1303

Optimisation of Carotid Artery Plaque Imaging Using IMSDE Blood Suppression

Chengcheng Zhu1, Andrew J. Patterson1, Martin John Graves1, Jonathan H. Gillard1

1University Department of Radiology, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom

Improved motion-sensitized driven-equilibrium (iMSDE) preparation provides better blood suppression than traditional spatial saturation and double inversion-recovery (DIR) methods in carotid vessel wall imaging. However, iMSDE preparation can cause signal loss, mostly due to eddy current effects and B1+ inhomogeneity. We have investigated the CNR and SNR performance of iMSDE prepared T1w and T2w MRI using composite RF pulses and sinusoidal gradients.